apalutamide will lessen the level or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Coadministration of apalutamide, a robust CYP3A4 inducer, with medicine which have been CYP3A4 substrates can result in reduce publicity to these medicines.Disorders OF USE: The knowledge On this